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PART I QUESTIONS Introducing Developmental Biology 1

CHAPTER 1 Developmental Anatomy 5

CHAPTER 2 Developmental Genetics 31

CHAPTER 3 Cell-Cell Communication in Development 69

PART Ⅱ SPECIFICATION Introducing Cell Commitment and Early Embryonic Development 109

CHAPTER 4 Fertilization 121

CHAPTER 5 Early Development in Selected Invertebrates 159

CHAPTER 6 The Genetics ofAxis Specification in Drosophila 203

CHAPTER 7 Amphibians and Fish 241

CHAPTER 8 Birds and Mammals 287

PART Ⅲ THE STEM CELL CONCEPT Introducing Organogenesis 323

CHAPTER 9 The Emergence of the Ectoderm 333

CHAPTER 1 0 Neural Crest Cells and Axonal Specificity 373

CHAPTER 11 Paraxial and Intermediate Mesoderm 413

CHAPTER 12 Lateral Plate Mesoderm and the Endoderm 445

CHAPTER 13 Development of the Tetrapod Limb 485

CHAPTER 14 Sex Determination 511

CHAPTER 15 Postembryonic Development 541

CHAPTER 16 The Saga of the Germ Line 583

PART Ⅳ SYSTEMS BIOLOGY Expanding Developmental Biology to Medicine, Ecology, and Evolution 617

CHAPTER 17 Medical Aspects of Developmental Biology 625

CHAPTER 18 Developmental Plasticity and Symbiosis 659

CHAPTER 19 Developmental Mechanisms of Evolutionary Change 683