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PART ONE GENES, CHROMOSOMES,AND HEREDITY 1

1 Introduction to Genetics 1

2 Mitosis and Meiosis 18

3 Mendelian Genetics 42

4 Extensions of Mendelian Genetics 71

5 Chromosome Mapping in Eukaryotes 105

6 Genetic Analysis and Mapping in Bacteria and Bacteriophages 143

7 Sex Determination and Sex Chromosomes 174

8 Chromosome Mutations: Variation in Number and Arrangement 197

9 Extranuclear Inheritance 221

PART TWO DNA: STRUCTURE,REPLICATION, AND VARIATION 238

10 DNA Structure and Analysis 238

11 DNA Replication and Recombination 269

12 DNA Organization in Chromosomes 294

PART THREE GENE EXPRESSION,REGULATION, AND DEVELOPMENT 315

13 The Genetic Code and Transcription 344

14 Translation and Proteins 344

15 Gene Mutation, DNA Repair,and Transposition 374

16 Regulation of Gene Expression in Prokaryotes 403

17 Regulation of Gene Expression in Eukaryotes 426

18 Developmental Genetics 451

19 Cancer and Regulation of the Cell Cycle 473

SPECIAL TOPICS IN MODERN GENETICS 493

Ⅰ DNA Forensics 493

Ⅱ Genomics and Personalized Medicine 504

Ⅲ Epigenetics 517

Ⅳ Stem Cells 529

PART FOUR GENOMICS 545

20 Recombinant DNA Technology 545

21 Genomics, Bioinformatics,and Proteomics 574

22 Applications and Ethics of Genetic Engineering and Biotechnology 621

PART FIVE GENETICS OF ORGANISMSAND POPULATIONS 659

23 Quantitative Genetics and Multifactorial Traits 659

24 Genetics of Behavior 680

25 Population and Evolutionary Genetics 697

26 Conservation Genetics 725