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Part Ⅰ Chemical and Molecular Foundations 1

1 Molecules, Cells, and Evolution 1

2 Chemical Foundations 23

3 Protein Structure and Function 59

Part Ⅱ Genetics and Molecular Biology 115

4 Basic Molecular Genetic Mechanisms 115

5 Molecular Genetic Techniques 171

6 Genes, Genomics, and Chromosomes 223

7 Transcriptional Control of Gene Expression 279

8 Post-transcriptional Gene Control 345

Part Ⅲ Cell Structure and Function 397

9 Culturing, Visualizing, and Perturbing Cells 397

10 Biomembrane Structure 443

11 Transmembrane Transport of Ions and Small Molecules 473

12 Cellular Energetics 517

13 Moving Proteins into Membranes and Organelles 577

14 Vesicular Traffic, Secretion, and Endocytosis 627

15 Signal Transduction and G Protein-Coupled Receptors 673

16 Signaling Pathways That Control Gene Activity 721

17 Cell Organization and Movement I: Microfilaments 773

18 Cell Organization and Movement Ⅱ: Microtubules and Intermediate Filaments 821

19 The Eukaryotic Cell Cycle 873

Part Ⅳ Cell Growth and Development 925

20 Integrating Cells Into Tissues 925

21 Stem Cells, Cell Asymmetry, and Cell Death 977

22 Nerve Cells 1019

23 Immunology 1059

24 Cancer 1113