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PART Ⅰ AN INTRODUCTION TO IMMUNOBIOLOGY AND INNATE IMMUNITY 1

Chapter 1 Basic Concepts in Immunology 1

Chapter 2 Innate Immunity: The First Lines of Defense 37

Chapter 3 The Induced Responses of Innate Immunity 75

PART Ⅱ THE RECOGNITION OF ANTIGEN 127

Chapter 4 Antigen Recognition by B-cell and T -cell Receptors 127

Chapter 5 The Generation of Lymphocyte Antigen Receptors 157

Chapter 6 Antigen Presentation to T Lymphocytes 201

PART Ⅲ THE DEVELOPMENT OF MATURE LYMPHOCYTE RECEPTOR REPERTOIRES 239

Chapter 7 Signaling Through Immune-System Receptors 239

Chapter 8 The Development and Survival of Lymphocytes 275

PART Ⅳ THE ADAPTIVE IMMUNE RESPONSE 335

Chapter 9 T Cell-Mediated Immunity 335

Chapter 10 The Humoral Immune Response 387

Chapter 11 Dynamics of Adaptive Immunith 429

Chapter 12 The Mucosal Immune System 465

PARTⅤ THE IMMUNE SYSTEM IN HEALTH AND DISEASE 509

Chapter 13 Failures of Host Defense Mechanisms 509

Chapter 14 Allergy and Allergic Diseases 571

Chapter 15 Autoimmunity and Transplantation 611

Chapter 16 Manipulation of the Immune Response 669

Appendix I Immunologist's Toolbox with Immunological Constants 717

Appendix Ⅱ CD Antigens 763

Appendix Ⅲ Cytokines and Their Receptors 779

Appendix V Chemokines and Their Receptors 782

Biographies 784

Glossary 786

Index 823