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Protein metabolism．Some problems brought into focus＆Opening remarks by A．QUERIDO 1

Action of hormones at the cellular level 8

The effect of growth hormone on protein synthesis＆by A．KORNER 8

Discussion:Dreyfus，Korner，Laron，Staehelin 22

Regulation of protein synthesis by androgens and estrogens＆by J．D．WILSON 26

Discussion:Aschkenasy，Kassenaar，Korner，Wilson 41

Histological aspects of the action of androgens and oestrogens＆by J．A．SZIRMAI 45

Discussion:Aschkenasy，Desaulles，Leathem，Querido，Szirmai，Tanner 75

General Discussion: 78

Introduction:The importance of experimental conditions for the demonstration of hormone effects in vitro and in vivo＆by W．DIRSCHERL 78

Arias，Korner，Laron，Leathem，Querido，Raben，Szirmai，Tuchmann-Duplessis，Wilson 86

Factors influencing protein metabolism in the organism 90

Protein malnutrition and replenishment with protein in man and animals＆by J．C．WATERLOW 90

Discussion:Aschkenasy，Fraser，Hoffenberg，Querido，Rundles，Schreier，Waterlow 105

The bearing of the plane of nutrition on growth and endocrine development＆by R．A．McCANCE and E．M．WIDDOWSON 109

Discussion:Bauer，McCance，Prader，Schreier Tanner，Waterlow 118

Metabolic effects of growth hormone in man＆by M．S．RABEN，P．R．MINTON，M．L．MITOHELL，and H．JUAREZ-PENALVA 121

Discussion:Ikkos，Querido，Raben，Young 134

Nitrogen balance studies:the relation of protein metabolism to excessive shifts of sodium and potassium＆by P．S．BLOM，J．DE GRAEFF，A．A．H．KASSENAAR，and H．A．SONNEVELDT 137

Studies of protein metabolism in humans with the aid of N15-labelled glyeine＆by A．HAAK，A．A．H．KASSENAAR，and A．QUERIDO 150

Discussion:Blom，Fraser，Haak，kassenaar，Querido，Tremolières，Waterlow 158

General Discussion: 161

Introduction:Homoeostasis in protein metabolism＆by J．TREMOLIEBES 161

Ikkos，Laron，Prader，Raben，Schreier，Staehelin 167

Evaluation and mode of action of anabolic steroids 170

Differentiation of action of various anabolic steroids＆by P．A．DESAULLES and C．KRAHENBUHL 179

Evaluation of long-acting anabolic steroids＆by G．A．OVERBEEK，J．VAN DER VIES，and J．DE VISSER 185

Discussion:Aschkenasy，Desaulles，Fraser，Gross，Kassenaar，Korner，Overbeek，Querido，Raben 196

The influence of nutrition and nutritional status on the effect of androgens and anabolic agents＆by J．H．LEATHEM 202

Discussion:Korner，Leathem，Overbeek，Querido，Sala，Waterlow，Young 219

Effects of anabolic steroids on nucleic acid and protein metabolism＆by A．A．H．KASSENAAR，A．QUERIDO，and A．HAAK 222

Discussion:Arias，Dirscherl，Dreyfus，de Jongh，Kassenaar，Korner，Overbeek，Querido，Szirmai，Tremolières，Wilson 234

Effect of steroids on bone formation＆by K．KOWALEWSKI 238

Discussion:Desaulles，Dymling，Gross，Kowalewski，Laron，Overbeek，Vermeulen 263

General Discussion: 268

Introduction:Effects of protein deficiency on the endoerine system＆by A．ASCHKENASY 268

Aschkenasy，Desaulles，Dreyfus，Gross，Overbeek，Querido，Tanner，Vermeulen 272

Protein metabolismm in human pathological states 275

The effect of injury upon human protein metabolism＆by J．M．KINNEY 275

Discussion:Fraser，Gemzell，Ikkos，Kinney，McCance，Tuchmann-Duplessis，Young 297

Human liver cirrhosis secondary to nutritional deficiency＆by R．SUBRAMANLAM 300

Discussion:Arias，Hoffenberg，Kowalewski，Prader，Subramaniam，Tremolières，Waterlow 310

I131-albumin metabolism in human adults after experimental protein depletion and repletion＆by R．HORRENBERG，S．SAUNDERS，G．C．LINDER，E．BLACK，and J．F．BROOK 314

Discussion:Arias，Aschkenasy，Fraser，Hoffenberg，Ikkos，Querido，Schreier，Waterlow 323

Muscular protein metabolism in normal and diseased states＆by J．-C．DREYFUS，J．KRUH，and G．SCHAPIRA 326

Discussion:Arias，Dreyfus，Kassenaar，Korner，Prader，Querido，Stachelin 350

General Discusson: 352

Introduction:Some aspcets of protein metabolism in surgical trauma and injury＆by K．SCHREIER 352

Blom，Dreyfus，Kinney，Korner，Querido，Rittenberg，Sohreier，Tremolières，Waterlow，Wilson，Young 355

The effects of anabolic agents in man 361

The evaluation of growth and maturity in children＆by J．M．TANNER 361

Use of anabolic agents in disorders of growth＆by A．PRADER and R．ILLIG 383

Discussion:Gemzell，Haak，Laron，Prader，Querido，Raben，Tanner，van der Werff tan Bosch 398

Definition，aetiology，and effects of osteopenia＆by G．C．H．BAUER 405

Anabolic steroids in the treatment of osteopenia＆by J．-F．DYMLING，B．ISAKSSON，and B．SJOGREN 412

Discussion:Bauer，Dymling，Hoffenberg，McCance，Querido 424

General Discussion: 427

Introduction:Some endocrine aspects of growth and bone＆by T．R．C．FRASER 427

Bauer，Fraser，Tanner 431

The effects of anabolic steroids on liver function＆by I．M．ARIAL 434

Discussion:Arias，Dreyfus，Gross，Leathem，Mandema，Overbeek，Subramaniam，Vermeulen 446

Anabolic steroids in the treatment of renal failure＆by J．HESS THAYSEN 450

Discussion:Aschkenasy，Labhart，McCance，Querido，Thaysen，Waterlow 479

Action of anabolic steroids on red-cell production＆by R．W．RUNDLES 482

Discussion:Arias，Aschkenasy，Desaulles，Gemzell，Gross，Kassenaar，Leathem，Mandema，Prader，Rundles 488

Concluding Discussion: 494

Desaulles，Dreyfus，Korner，Laron，Leathem，McCance，Overbeek，Preader，Querido，Raben，Thaysen，Tremolières，Wilson 494

Summing up＆by F．G．YOUNG 500

List of authors 506

Subject index 507