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PART Ⅰ．BIOLOGY 1

1．Experimental Cutaneous Carcinoma＆Harold L．Stewart 3

2．Pulmonary Tumors in Mice＆Harold L．Stewart 18

3．Morphology of Mammary Tumors in Mice＆Thelma B．Dunn 38

4．The Histopathology of Experimental Tumors of the Liver of the Rat＆Harold L．Stewart and Katharine C．Snell 85

5．Genetics of Neoplasia＆Clarence Cook Little 127

6．Hormonal Factors in Experimental Carcinogenesis＆William U．Gardner Carroll A．Pfeiffer John J．Trentin 152

7．Virus-Induced Tumors and the Virus Theory of Cancer＆Francisco Duran-Reynals 238

8．Transplantable Tumors＆George D．Snell 293

9．Heterologous Transplantation＆Helene Wallace Toolan 346

10．Physiopathology of Leukemia＆Jacob Furth Mario Baldini 364

11．Uses of Tissue Culture in the Study of Malignancy＆Margaret R．Murray 469

PART Ⅱ．CHEMISTRY AND PHYSICS 517

12．Nutrition and Cancer＆Albert Tannenbaum 517

13．The Chemical and Genetic Mechanisms of Carcinogenesis:Ⅰ．Nature and Mode of Action＆Alexander Haddow 565

14．The Chemical and Genetic Mechanisms of Carcinogenesis:Ⅱ．Biologic Alkylating Agents＆Alexander Haddow 602

15．The Chemistry of Cancer Tissue＆Richard J．Winzler 686

16．Nucleoproteins and Cancer＆Gerhard Schmidt 707

17．Enzymes and Cancer＆William H．Fishman 732

18．Cancer Cytochemistry and Histochemistry＆Robert C．Mellors 761

19．Experimental Cancer Chemotherapy＆David A．Karnofsky 783

20．Radiation and Cancer:Experimental Studies＆Leonidas D．Marinelli Austin M．Brues 831

PART Ⅲ．CLINICAL INVESTIGATION 853

21．Natrual History of Neoplastic Disease＆Michael B．Shimkin 855

22．Steroid Hormone Metabolism in Cance＆Lewis L．Engel 872

23．Clinical Investigation in Cancer Researc＆Freddy Homburger 890

24．Environmental Cancer＆Wilhelm C．Hueper 919

Smoking and Lung Cancer＆Morton L．Levin and Paul R．Gerhardt 971

25．Statistical Studies in Cancer＆Herbert L．Lombard 974

PART Ⅳ．PRACTICAL APPLICATIONS 1011

26．Clinical Cancer Chemotherapy＆Alfred Gellhorn 1013

27．Applied Exfoliative Cytology＆S．Charles Kasdon 1086

28．Applied Radiation Therapy＆L．Henry Garland 1116

INDEX 1169