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PART ONE Methods of Blood Collection and Plasma Fractionation 1

Ⅰ Blood Collection＆Robert B．Pennell 3

Ⅱ Plasma Proteins and Plasma Fractionation＆J．L．Oncley 13

PART TWO Hormones of Pancreatic Origin 47

Ⅲ Insulin-like Activity and Anti-Insulin Factors in Human Plasma 49

Introduction＆Albert E．Renold 51

1．Insulin Bioassays in Vivo＆Paul M．Beigelman 53

2．Insulin Bioassays in Vitro:Using Isolated Rat Diaphragm＆A．F．Willebrands and J．J．Groen 60

3．Insulin Bioassays in Vitro:Using Isolated Rat Adipose Tissue＆Donald B．Martin,Yves M．Dagenais and Albert E．Renold 76

4．Immunoassay of Insulin＆Solomon A．Berson and Rosalyn S．Yalow 86

5．Anti-Insulin Factors＆Maurice E．Krahl 95

6．The State of Insulin in Human Plasma＆Harry N．Antoniades,Paul M．Beigelman,and Albert E．Renold 101

Ⅳ Glucagon in Plasma＆Maynard H．Makman,Richard S．Makman and Earl W．Sutherland 119

PART THREE Hormones of Pituitary Origin 139

Ⅴ The Detection of Growth Hormone in Plasma＆Ernst Knobil and Roy O．Greep 141

Ⅵ Adrenocorticotropic Hormone＆Paul L．Munson 149

Ⅶ Pituitary Gonadotropins＆Janet W．McArthur 191

Ⅷ Thyrotropic Hormone(s)＆John F．Crigler,Jr． 201

Ⅸ Vasopressin and Oxytocin in the Plasma of Man and Other Mammals＆Henry D．Lauson 225

PART FOUR Steroid Hormones 295

Ⅹ Androgens in Human Plasma＆Claude J．Migeon 297

Ⅺ Corticosteroids in Blood 333

1．Hormonal Secretion of the Adrenal Cortex＆Don H．Nelson 335

2．Methods for Measurement of Corticosteroids in Blood＆Kristen Eik-Nes 351

3．The Influence of Extra-Adrenal Factors on Blood Corticosteroids＆Avery A．Sandberg 363

Ⅻ Estrogens in Plasma＆Lewis L．Engel and Clive B．Cameron 399

ⅩⅢ Progesterone＆William H．Pearlman 415

ⅩⅣ The Binding of Steroid Hormones and Their Metabolites＆by Plasma Proteins 455

1．The Binding of Steroid Hormones and Their Metabolites＆by Plasma Proteins in Vivo Harry N．Antoniades 456

2．The Binding of Estrogens,Androgens and Progesterone＆by Plasma Proteins in Vitro W．Roy Slaunwhite,Jr． 478

3．The Binding of Corticosteroids＆by Serum Proteins in Vitro William H．Daughaday 495

PART FIVE Hormones Produced by Thyroid Gland,Adrenal Medulla and Placenta 513

ⅩⅤ Thyroid Hormones＆Sidney H．Ingbar and Norbert Freinkel 515

ⅩⅥ Epinephrine and Norepinephrine＆Marthe Vogt 581

ⅩⅦ Gonadotropins of Extra-Pituitary Origin＆Janet W．McArthur 599

INDEXES 631

Author Index 631

Subject Index 659