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General Cell Theory and Drug Design＆By J．F．DANIELLI 1

Lethal Synthesis＆By SIR RUDOLPH ALBERT PETERS 11

Detoxication Mechanisms and the Design of Drugs＆By R．T．WILLIAMS 21

Feedback Mechanisms in Biological Synthesis＆By BORIS MAGASANIK 39

Nucleic Acid Synthesis and Mechanism of Action of Fluorophyrimidines＆By CHARLES HEIDELBERGER 47

Enzymatic Interactions between Steroid Hormones and Pyridine Nucleotides＆By PAUL TALALAY 59

The Induction of Pinocytosis＆By H．HOLTER 77

Ion Transport Mechanisms＆By HANS H．USSING 89

Lysosomes and Chemotherapy＆By C．DE DUVE 101

Oxydation de Substrats Organiques par les Peroxydes Organiques＆By PIERRE DEMERSEMAN 113

Tritium Radiotherapy＆By WALTER G．VERLY 119

Peptides and Macromolecules as Carriers of Cytotoxic Groups＆By F．BERGEL,J．A．STOCK AND ROY WADE 125

An Approach to the Creation of Antitumour Drugs with Diverse Action Spectra＆By L．F．LARIONOV 139

Biological Aspects of Chemotherapy with Folic Acid Antagonists＆By W．JACOBSON 149

A Procedure for the Evaluation of Specific Effects of Antitumour Drugs＆By S．GARATTINI AND V．PALMA 167

Protection and Restoration of Bone Marrow in Laboratory Animals Following Administration of Radiomimetic Drugs＆By J．MAISIN 187

Population Changes and Drug Resistance in Tumours＆By GEORGE KLEIN 201

The Isoantigens of Malignant Cells＆By P．A．GORER 219

An Immunological Approach to tumour Growth Control＆By L．A．ZILBER 231

Modifications Antigéniques en Culture Tissulaire＆By P．DE SOMER AND A．PRINZIE 245

Biological Foundation of Cancer Control by Hormones＆By JACOB FURTH AND UNTAE KIM 259

Hormone Dependence and Autonomy＆By O．MUHLBOCK AND R．VAN NIE 277

Cytotoxic Hormones＆By H．LETTRE 285

The Possible Role of Electron Microscopy in the Study of the Biological Aspects of Cancer Chemotherapy＆By FRANCOISE HAGUENAU 295

Electron Microscopic Studies on the Process of Vacuole Formation Induced by Plant Polysaccharides in Ascites Tumour Cells＆By ALBERT J．DALTON AND MORRIS BELKIN 317

Relation of Viral Functions to Cancer Chemotherapy＆By S．E．LURIA 337

Tolerance and Interference＆By R．J．C．HARRIS 351

Carcinolytic Viruses＆By ALICE E．MOORE 365

The Connective Tissue Substrate＆By B．MCLOUGHLIN 371

Anticarcinogenesis＆By RIOJUN KINOSITA 387

Prophylaxis＆By J．MAISIN AND G．LAMBERT 399

AUTHOR INDEX 419