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Ⅰ. CARDIOVASCULAR DISEASES Udho Thadani part editor 3

1. Cardiac Arrhythmias and Conduction Disturbances Karen J. Beckman and Ralph Lazzara 3

2. Myocardial Performance: Systolic and Diastolic Function Eliot Schechter 13

3. Common Forms of Volume and Pressure Overload: Valvular Heart Disease Eliot Schechter 25

4. Congenital Heart Disease and Intracardiac Shunts Edward Overholt 35

5. Myocardial Ischemia and Infarction Udho Thadani 43

6. Cardiomyopathies Chittur A. Sivaram 55

7. Pulmonary Heart Disease Karen K. Hamilton 63

8. Pericardial Disease Edwin G. Olson 71

9. Infective Endocarditis Chittur A. Sivaram and Douglas P. Fine 83

10. Congestive Heart Failure Udho Thadani 91

11. Shock Syndrome Karen K. Hamilton 101

12. Hypertension David C. Kem 109

13. Peripheral Vascular Disease Brian G. Birdwell and Thomas L. Whitsett 117

14. Cardiovascular Wellness, Exercise, and Prevention of Heart Disease E. Randy Eichner 129

Part Ⅰ Questions: Cardiovascular Diseases 139

Ⅱ. DIGESTIVE DISEASES AND NUTRITION Richard F. Harty part editor 143

15. Esophagus Donald J. Kastens 143

16. Stomach and Duodenum Paul N. Maton 151

17. Pancreas Robert A. Rankin 161

18. Liver and Biliary Tract Richard F. Harty 169

19. Small Intestine Anil Minocha 187

20. Colon Richard F. Harty and Harry S. Ojeas 199

21. Clinical Nutrition Marie A. Bernard and Ralph T. Guild Ⅲ 211

Part Ⅱ Questions: Digestive Diseases and Nutrition 217

Ⅲ. ENDOCRINE AND METABOLIC DISORDERS David C. Kern part editor 221

22. Hormone Action R. Hal Scofield 221

23. Adrenal-ACTH Dale A. Freeman 231

24. Diabetes Mellitus and Glucose Metabolism Leann Olansky 239

25. Reproductive System Dale A. Freeman 249

26. Anterior and Posterior Pituitary Matthew T. Draelos 257

27. Thyroid R. Hal Scofield 267

28. Metabolic Bone Disease Mary Zoe Baker 277

Part Ⅲ Questions: Endocrine and Metabolic Disorders 285

Ⅳ. HEMATOLOGIC AND NEOPLASTIC DISORDERS James N George part editor 289

29. Red Cells, Anemia, and Erythrocytosis Sylvia S. Bottomley 289

30. Disorders of Myelopoiesis Dennis L. Confer 303

31. Lymphocytes and Lymphoproliferative Disorders Regina Resta and Michael A. Kolodziej 313

32. Oncogenesis and the Genetic Basis of Cancer Thomas H. Carter 325

33. Cancer: Biology and Clinical Course Vikki A. Canfield 339

34. Hemostasis and Thrombosis James N. George 347

Part Ⅳ Questions: Hematologic and Neoplastic Disorders 359

35. Organization of the Immune System: Mechanisms of Immune Injury John B. Harley 363

Ⅴ. RHEUMATOLOGIC AND IMMUNOLOGIC DISORDERS Morris Reichlin part editor 363

36. Immediate Hypersensitivity Diseases James H. Wells 375

37. Allergic Respiratory Diseases James H. Wells 385

38. Systemic Rheumatic Diseases Morris Reichlin 397

39. Immunodeficiency Samuel R. Oleinick 405

40. Osteoarthritis Haraldine A. Stafford 417

41. Rheumatoid Arthritis Leslie S. Staudt 427

42. Gout and Crystal Disease Ira N. Targoff 437

Part Ⅴ Questions: Rheumatologic and Immunologic Disorders 449

43. Pulmonary Gas Exchange D. Robert McCaffree 453

Ⅵ. PULMONARY DISEASES Paul V. Carlile part editor 453

44. Respiratory System Mechanics Paul V. Carlile 465

45. Control of Breathing Barry A. Gray 477

46. Diseases of Air Flow Limitation David C. Levin 491

47. Interstitial Lung Disease Martin H. Welch 501

48. Pulmonary Edema Barry A. Gray 513

49. Diseases of the Pleural Space Gary T. Kinasewitz 525

50. Venous Thromboembolism Brent R. Brown 533

Part Ⅵ Questions: Pulmonary Diseases 543

Ⅶ. RENAL AND ELECTROLYTE DISORDERS Chris E. Kaufman part editor 547

51. Disorders of Sodium and Water Metabolism Chris E. Kaufman 547

52. Disorders of Potassium Homeostasis Satish Kumar 557

53. Acid-Base Disturbances James A. Pederson 569

54. Disorders of Calcium, Phosphate, and Magnesium James E. Bourdeau 581

55. Glomerular Disorders Sudhir K. Khanna 595

56. Acute Renal Failure Laura I. Rankin 605

57. Chronic Renal Failure James E. Bourdeau and Chris E. Kaufman 615

58. Tubulointerstitial Disorders Sudhir K. Khanna 627

Part Ⅶ Questions: Renal and Electrolyte Disorders 635

Ⅷ. NEUROLOGIC DISEASES AND SPECIAL SENSES Peggy J. Wisdom part editor 639

59. Disorders of Consciousness and Cognition Peggy J. Wisdom 639

60. The Motor System Farhat Husain and Julie T. Parke 651

61. The Sensory System Osvaldo H. Perurena 667

62. The Extrapyramidal System Gary B. Bobele 679

63. The Cerebellar System Sanford Schneider 689

64. The Special Senses and Oculomotor System Bradley K. Farris,Keith F. Clark,and Gary W. Harris 695

65. Disorders of Cerebrospinal Fluid and Intracranial Pressure Mary K. Gumerlock 711

66. Seizures and Epllepsy Jeanne A. King 719

67. Head Pain and Cranial Neuralgia James R. Couch, Jr. 729

68. Cerebrovascular Disorders Michael R. Hahn and L. Philip Carter 739

69. Infectious of the Central Nervous System Richard W. Leech and Roger A. Brumback 753

Part Ⅷ Questions: Neurologic Diseases and Special Senses 763

Answers 765

Index 773