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1．DIGESTION AND ABSORPTION 1

Early experiments 1

Site of absorption 2

Digestion 3

Action of pancreatic lipase 5

Participation of phospholipids 7

Origin and fate of glycerol 9

Determination of state of absorption 10

Absorption of fatty acids as phospholipids 11

Absorption of fatty acids as sterol esters 12

2．TRANSPORT,DEPOSITION AND MOBILIZATION OF FATTY ACIDS 15

Blood transport 15

Deposition 18

Mobilization 21

3．TURNOVER AND METABOLIC INFLUENCES 23

Turnover studies 23

Turnover experiments with acetate 26

Turnover experiments with fatty acids 29

Relationships of carbohydrate and fatty acid metabolism 31

Hormonal influences 34

Fatty acid metabolism in tumors 34

4．BETA OXIDATION OF FATTY ACIDS 37

Acetoacetate formation 37

Conversion to carbohydrate 42

Fatty acid oxidation in plants 43

5．INTERCONVERSIONS OF FATTY ACIDS 46

The saturated and monounsaturated acids 46

The polyunsaturated acids 51

6．BIOSYNTHESIS 57

Fatty acid synthesis in animals 57

Fatty acid synthesis in plants 68

7．PHOSPHOLIPIDS 72

Biosynthesis 74

Catabolism 80

Function 82

8．STEROL ESTERS 88

Sterol esterification during absorption 90

Blood sterol and sterol esters 95

Liver sterol esters 98

Fatty acid spectra of sterol esters 99

9．PROSPECTUS 104

Appendix Ⅰ．Preparation of labeled fatty acids 108

Biosynthesis 108

Laboratory synthesis 110

Appendix Ⅱ．Controlled degradation of labeled fatty acids 119

AUTHOR INDEX 131

SUBJECT INDEX 137