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PART Ⅰ HISTOPATHOLOGICAL REACTIONS OF MUSCLE 1

CHAPTER 1．STRUCTURAL CHANGES IN THE MUSCLE FIBRE：LOSS OF CROSS-STRIATION，CLOUDY AND GRANULAR CHANGES，FLOCCULAR CHANGES AND PHAGOCYTOSIS 1

CHAPTER 2．CHANGES IN MUSCLE NUCLEI 12

CHAPTER 3．CHANGES IN FIBRE SIZE 19

CHAPTER 4．BASOPHILIC FIBRES WITH VESICULAR NUCLEI AND PROMINENT NUCLEOLI 25

CHAPTER 5．RINGED FIBRES 32

CHAPTER 6．SARCOPLASMIC MASSES 38

CHAPTER 7．CHANGES IN INTERSTITIAL TISSUES：COLLAGEN AND FAT 45

CHAPTER 8．LEUCOCYTIC INFILTRATIONS 49

CHAPTER 9．CHANGES IN MUSCLE SPINDLES AND PERIPHERAL MUSCULAR NERVES 56

CHAPTER 10．PATTERN OF LESION 60

PART Ⅱ CLINICO-PATHOLOGICAL CORRELATIONS 65

CHAPTER 11．CLINICAL CLASSIFICATION OF NEUROMUSCULAR DISEASES 67

CHAPTER 12．DISTAL MUSCULAR SYNDROMES．LARGE GROUPS OF SMALL FIBRES AND ABNORMAL PERIPHERAL MUSCULAR NERVES AND MUSCLE SPINDLES 70

CHAPTER 13．MYOTONIC SYNDROMES，RINGED FIBRES，SARCOPLASMIC MASSES AND INTERNAL NUCLEI 80

CHAPTER 14．PROXIMAL MUSCULAR SYNDROMES．ABNORMALLY LARGE FIBRES，STRUCTURAL CHANGES，PHAGOCYTOSIS，BASOPHILIC FIBRES WITH VESICULAR NUCLEI AND PROMINENT NUCLEOLI，LEUCOCYTIC INFILTRATIONS AND ABNORMAL COLLAGEN AND FAT 84

CHAPTER 15．MYASTHENIA GRAVIS：LYMPHORRHAGES AND OTHER ABNORMALITIES 92

SUMMARY 95

CONCLUSIONS 96

APPENDIX Ⅰ：METHODS AND TECHNIQUES 97

APPENDIX Ⅱ：CROSS-INDEX OF CASES 98

BIBLIOGRAPHY AND REFERENCES 101

INDEX 102