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Ⅰ．Structure and Genetics of Immune-Globulins 13

Genetically Determined Structures of Immune-Globulins＆Morten Harboe and C．Kirk Osterland 13

The γ-Globulin Groups in Man-Their Structural Basis and Biologic Significance＆E．C．Franklin，H．Fudenberg，L．Martensson，M，Meltzer and D．R．Stanworth 25

Immunochemical Studies on Antigenic Structure of Human γ-and β2-Globulins＆P．Burtin 38

Two Types of Molecules(Ⅰ and Ⅱ)present in the four Major γ-Globulin Groups＆John L．Fahey 50

Unresolved Problems in the Analysis of the Structure of Antibodies＆Gerald M．Edelman 57

Discussion on Structure and Genetics of Immune-Globulins 68

Ⅱ．Antibody Formation 79

Antibody Formation in Vitro＆M．Fishman and F．L．Adler 79

The Origin of Antibody-Forming Cells＆J．L．Gowans and D．D．McGregor 89

Cytokinetics of Antibody Response＆T．Makinodan and J．F．Albright 99

The Nature of RNA Synthesis in Immune Induction＆G．J．V．Nossal and Judith Mitchell 113

Antibody Formation to Bacteriophage ？X 174＆Jonathan W．Uhr and Martin S．Finkelstein 127

Discussion on Antibody Formation 136

Ⅲ．Influence of Various Factors on Antibody Response 148

Critical Factors Governing the Response Pattern：Immunity versus Tolerance＆Milan Hasek 148

X-Ray Enhancement of Antibody Formation＆Frank J．Dixon and Patricia J．McConahey 158

Autoimmunity and Termination of Acquired Immunological Tolerance＆William O．Weigh 167

Studies on the Role of the Thymus in Developmental Biology，with a Consideration of the Association of Thymus Abnormalities and Clinical Disease＆Robert A．Good，Carlos Martinez，Agustin P．Dalmasso，Ben W．Papermaster and Ann E．Gabrielsen 177

Discussion on Influence of Various Factors on Antibody Response 201

Ⅳ．Mechanisms of Immunogenic Kidney Diseases 208

Specific Nephrotoxic Nephritis：Old Facts and Present Concepts＆B．C．Seegal，K．C．Hsu and G．A．Andres 208

Demonstration of and Evidence for the Lymphocyte Bound Nature of a Secondary Nephritis Producing Factor in Nephrotoxic Glomerulonephritis in Rats＆E．F．Pfeiffer 220

Experimental Autoimmune Renal Disease in Rats＆Walter Heymann，E．P．Kmetec，S．G．F．Wilson，J．L．P．Hunter，Donald B．Hackel and Francis Cuppage 240

Glomerulonephritis Induced in Sheep and Monkeys by Injections of Heterologous Glomerular Basement Membrane and Freund＇s Adjuvant＆Raymond W．Steblay 252

Pathogenesis of Ultrastructural Glomerular Changes induced by Immunologic Means＆Joseph D．Feldman 263

Antigenic Components of Hemolytic Streptococci＆Richard M．Krause 282

Discussion on Mechanisms of Immunogenic Kidney Diseases 290

Ⅴ．Mechanisms of Blood Cell Damage Produced by Immunological Reactions 300

Mechanisms of Immune Injury in Mammalian Cell Systems＆Burton Goldberg 300

Mechanism of Elimination of Sensitized Rat Erythrocytes and E．Coli from the Circulation of Mice＆P．A．Miescher，H．L．Spiegelberg and B．Benacerraf 311

Observations on the Immunochemical Nature of Red Cell Autosensitization＆J．P．Leddy，R．W．Hill，S．N．Swisher and J．H．Vaughan 318

Identification of Complement Antigens Coating Red Cells in Acquired Hemolytic Anemia＆H．J．Muller-Eberhard 332

Mechanism of Blood Cell Damage by Adsorption of Antigen-Antibody Complexes＆N．Raphael Shulman 338

Reticuloendothelial Proliferation Stimulated by Injured，Autologous Red Cells＆James H．Jandl，Harry S．Jacob and Richard A．MacDonald 353

Discussion on Mechanisms of Blood Cell Damage Produced by Immunological Reactions 369

Index 387