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Part Ⅰ．Fundamental Concepts 3

Historical Perspectives on Trophoblast and its Tumors＆By WILLIAM B．OBER 3

The Biology of Trophoblast＆By BENT G．BOVING 21

Homoplastic Implantation of Toadfish(Opsanus tau) Embryos in the Peritoneal Cavity of an Adult Fish＆By PAUL S．GALTSOFF and EUGENIA GALTSOFF 44

Trophoblast：Problems of Invasion and Transport＆By ROBERT W．NOYES 54

Hormonal Actions of Chorionic Gonadotropin＆By JOSEPH THOMAS VELARDO 65

Part Ⅱ．Hydatidiform Mole 86

Genesis of Hydatidiform Mole：Old and New Concepts＆By HENRY W．EDMONDS 86

Problems in the Classification of Hydatidiform Moles＆By J．SMALBRAAK 105

Management of Patients with Hydatidiform Mole＆By C．LEE BUXTON 121

Chorionic Gonadotrophin Determinations in Patients with Hydatidiform Mole and Choriocarcinoma＆By E．DELFS 125

Part Ⅲ．Trophoblastic Tumors 140

The Albert F．Mathieu Chorionepithelioma Registry＆By JOHN I．BREWER 140

Chorioadenoma Destruens＆By R．R．GREENE 143

Aspects of Choriocarcinoma in the Female＆By W．WALLACE PARK 152

Choriocarcinoma of the Testis and Extragenital Choriocarcinoma in Men＆By NATHAN B．FRIEDMAN 161

Geographic Variation in the Occurrence of Hydatidiform Mole and Choriocarcinoma＆By THE JOINT PROJECT FOR STUDY OF CHORIOCARCINOMA AND HYDATIDIFORM MOLE IN ASIA 178

The Natural History of Choriocarcinoma：Problems of Immunity and Spontaneous Regression＆By WADI A．BARDAWIL AND BENJAMIN L．TOY 197

Chemotherapy of Choriocarcinoma and Related Trophoblastic Tumors in Women＆By ROY HERTZ，DELBERT M．BERGENSTAL，MORTIMER B．LIPSETT，EDWARD B．PRICE，and THEODORE F．HILBISH 262