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General Review of Cancer Therapy＆WILLIAM H．WOGLOM 1

The Transparent Chamber Technique as a Tool in Experimental Tumor Therapy＆GLENN H．ALGIRE 13

Some Cellular and Surface Chemical Aspects of Tumor Chemotherapy＆M．J．KOPAC 27

A Method of Producing Oncolysis in Rats That Conferred a Certain Immunity Against Homologous Tumors＆PAUL APTEKMAN 58

The Chemistry of Substances Specific for the Stimulation of Lymphopoiesis and Myelopoiesis＆D．L．TURNER AND F．R．MILLER 64

A Myeloid Metaplasia Factor from Human Urine＆R．W．HEINLE，H．HIRSCHMANN，AND J．T．WEARN 77

The Role of Nutrition in the Origin and Growth of Tumors＆ALBERT TANNENBAUM 96

The Influence of Diet on the Production of Hepatic Tumors Induced by p-Dimethylaminoazobenzene＆EUGENE L．OPIE 128

Chemotherapeutic Regressions of Transplanted and Spontaneous Cancers in Mice 139

Ⅰ．Review of the Work of the Laboratory，1937-1945＆RICHAED LEWISOHN 139

Ⅱ．Studies on Tumor Growth-Inhibitory Substances＆DANIEL LASZLO 148

Ⅲ．Results of Treatment of Spontaneous Tumors with ＂Folic Acid＂ and Allied Substances＆CECILIE LEUCHTENBERGER 157

Ⅳ．Histological Changes Occurring in Breast Cancers of Mice Treated with Folic Acid＆RUDOLF LEUCHTENBERGER 163

Effect of Intravenous Injection of Yeast and Barley Extracts and L．Casei Factor upon Spontaneous Mammary Adenocarcinoma in Mice＆KANEMATSU SUGIURA 208

Note：The Growth-Inhibition of Mouse Sarcoma 180＆PAUL A．ZAHL AND S．H．HUTNER 214

A Review of the Treatment of Malignant Tumors by Coley Bacterial Toxins＆HELEN COLEY NAUTS AND BRADLEY L．COLEY 217

Some Aspects of a Joint Institutional Research Program on Chemotherapy of Cancer：Current Laboratory and Clinical Experiments with Bacterial Polysaccharide and with Synthetic Organic Compounds 236

Ⅰ．Scope of the Program＆M．J．SHEAR 236

Ⅱ．Organic Chemistry＆JONATHAN L．HARTWELL 241

Ⅲ．Method Used in Screening Compounds for Potency＆VIRGINIA B．PETERS 244

Ⅳ．Cytopathology＆ALBERT J．DALTON 246

Ⅴ．Histopathology＆THELMA B．DUNN 248

Ⅵ．Protozoa and Cancer＆THEODORE HAUSCHKA 250

Ⅶ．Protozoan Metabolite Project＆CHARLES W．REES 258

Ⅷ．Nuclear Changes Produced by S．Marcescens (B．Prodigiosus) Polysaccharide＆IRENE COREY DILLER 260

Ⅸ．Temperature Changes Produced in Mice with S．Marcescens Polysaccharide＆LYLE V．BECK 265

Ⅹ．Preparation of Polysaccharide Solutions for Clinical Use and Tissue Culture Experiments＆JANE ROYLE MCCONNELL 271

Ⅺ．Reactions of Patients and of Tumors to Injection of S．Marcescens Polysaccharide in Eight Cases of Malignant Disease＆A．LEON HOLLOMAN 273

Ⅻ．Reactions of Patients to Injection of S．Marcescens Polysaccharide in Nine Further Cases of Malignant Disease＆R．OAKEY 277

ⅩⅢ．Clinical Pathological Considerations，and Resume＆STANLEY P．REIMANN 278

The Relation Between Chemical Constitution and Biological Action of the Nitrogen Mustards＆FREDERICK S．PHILIPS AND ALFRED GILMAN 285

Experimental Observations on the Use of the Nitrogen Mustards in the Treatment of Neoplastic Disease．D．A．Karnofsky，＆J．H．BURCHENAL，R．A．ORMSBEE，I．CORNMAN AND C．P．RHOADS 293

The Clinical Application of Methyl-Bis (β-Chloroethyl) Amine Hydrochloride to the Treatment of Lymphomas and Allied Dyscrasias＆CHARLES L．SPURR，LEON-0．JACOB-SON，TAYLOR R．SMITH AND E．S．GUZMAN BARRON 306

An Evaluation of Methyl-Bis(β-Chloroethyl) Amine Hydrochloride(Nitrogen Mustards)in the Treatment of Lymphomas，Leukemia and Allied Diseases． D．A．KARNOFSKY，L．F．CRAVER，C．P．RHOADS and J．C．ABELS，with the technical assistance of MYRTLE E．MCELROY…… 319

Use of Methyl-Bis(β-Chloroethyl) Amine Hydrochloride and Tris(β-Chloroethyl)Amine Hydrochloride(＂Nitrogen-Mustards＂) in the Therapy of Hodgkin’s Disease，Lymphosarcoma，Leukemia and Certain Allied and Miscellaneous Disorders．Louis S． GOODMAN，MAXWELL M．WINTROBE，MARGARET T．MCLENNAN，WILLIAM DAMESHEK，MORTON J． GOODMAN and MAJOR ALFRED GILMAN 338

Clinical Experiences with Nitrogen Mustard Therapy＆MAXWELL M．WINTROBE，MARGARET T．MCLENNAN and CHARLES M．HUGULEY，JR 347

Some Effects of Sulfur and Nitrogen Mustards on Cell Nuclei in Mammalian Cornea＆JONAS S．FRIEDENWALD，WILHELM BUSCHKE，ROY 0．SCHOLZ AND SYLVIA G．MOSES 358

Anti-Androgenic Treatment of Prostatic Carcinoma in Man＆CHARLES HUGGINS 379

The Treatment of Blood Dyscrasias，Lymphomas，and other Malignant Diseases with Radioactive Phosphorus：Clinical and Experimental Results＆EDWARD H．REINHARD AND NATHAN A．WOMACK 384

A Further Report on the Action of Urethane in Leukemia＆EDITH PATERSON，INEZ APTHOMAS，ALEXANDER HADDOW AND JEAN M．WATKINSON 401

Effects of Urethane upon Acute Lymphatic Leukemia in a Dog＆H．B．PARRY AND J．R．M．INNES 416

Treatment of Leukemia with 9，10-Dimethyl-l，2-Benzanthracene＆J．ENGELBRETH-HOLM AND S．STAMER 419

Administration of Oil-Soluble Organo-Metallic Compounds in Malignancy＆CHARLES F．GESCHICKTER AND E．EMMET REID 431